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Clinical manifestations of this infection are broad spectrum and can be very subtle; thus, a high degree of clinical suspicion and risk stratification are essential.
Aerosol generated during upper GI endoscopy is likely to be more infective than that generated during colonoscopy. Transmission in the endoscopy setting can also occur through inhalation of droplets and direct contact with contaminated body secretions.
European Centre for Disease Prevention and Control Guidance for wearing and removing personal protective equipment in healthcare settings for the care of patients with suspected or confirmed COVID-19.
The process of putting on the PPE is called “donning” and consists of 4 steps, as illustrated in Figure 6 and demonstrated in Video 1 (available online at www.VideoGIE.org). The process of taking off the PPE is called “doffing” and consists of 5 steps, as illustrated in Figure 6 and demonstrated in Video 1.
Figure 1Donning (putting on personal protective equipment) station. Red arrow indicates the endoscopy room location in relation to the donning area.
Figure 2Endoscopist wearing full personal protective equipment, including head cover, face shield (visor), filtering face piece mask respirator, full gown, and 2 sets of gloves.
Figure 5Doffing area, with 8 stations to facilitate proper methods for removing personal protective equipment after endoscopy. Red arrow indicates exit door to the clean area.
A lot of thought has to go into the placement of donning and doffing areas in relation to the endoscopy suite to avoid cross-contamination (Figs. 4 and 5). The endoscopy suites have to be completely stripped down, and only the most essential equipment required for that particular procedure should be kept inside (Fig. 3). We demonstrate the principles of this in our video.
The way endoscopes are held during the procedure can also be altered to minimize accidental splashing of fluid and release of air from the endoscope. The ports of the endoscopes can be covered by a plastic sleeve to contain any accidental leakage.
Finally, aerosol is generated during endoscopy for a variety of reasons, but a major contributing factor is air/Co2 insufflation during endoscopy. This leads to a buildup of positive pressure in the gut, resulting in intermittent release of aerosol. We have adapted our technique and replaced air/Co2 insufflation with water to minimize risk of aerosol generation. Underwater colonoscopy is widely practiced, so most clinicians can acquire these skills.
Special precautions need to be taken when doing underwater gastroscopy because of the risk of aspiration, and endotracheal intubation should be considered.
We acknowledge that the exact measures adopted by each unit will depend on a range of factors, including availability of PPE, logistics, and local protocols. However, our video should provide broad principles that can be adapted to suit local circumstances.