Sessile serrated lesions (SSLs) have a high risk of incomplete endoscopic resection.1 The benefit of using acetic acid spray has been reported for SSLs in the colon.2,3 Our previous experience has demonstrated that acetic acid spray, along with indigo carmine, is of substantial benefit for the delineation of SSLs.2 Similarly, the use of acetic acid for a single case of sessile serrated polyposis syndrome was reported and showed clinical usefulness.3