Gangliocytic paraganglioma (GP), biologically similar to pheochromocytoma, is a rare tumor predominant in the second portion of the duodenum.1 GP is histologically composed of 3 types of cells: epithelioid endocrine cells, ganglion-like cells, and spindle-shaped cells.2 Although EUS-guided FNA is useful for preoperative diagnosis, small biopsy specimens make diagnosis difficult. In some cases, surgery has been performed for diagnosis. Here, we report a case in which endoscopic papillectomy (EP) was used as a diagnostic modality.